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Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

null

《医学前沿（英文）》 2012年 第6卷 第4期   页码 406-410 doi: 10.1007/s11684-012-0217-3

摘要：

The esophagus is perfused directly by prominent arteries and may provide a more consistent tissue source for pulse oximetry. The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probe on patients during controlled hypoxemia in comparison to measurements obtained with conventional pulse oximetry (SpulseO2). Forty-five ASA I–II adult patients were included in this prospective observational study. Nellcor digital oximetric probes were placed on finger tips for SpulseO2 before anesthesia. After tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal oximetric monitoring (SoesO2). All patients were disconnected from the breathing circuit to establish a controlled hypoxemia, and were re-connected to the breathing circuit and ventilated with 100% oxygen immediately when SoesO2 dropped to 90%. Matched SoesO2 and SpulseO2 readings were recorded when SoesO2measurements were at 100%, 95%, 90% and the lowest reading. The time for SoesO2 and SpulseO2 to drop from 100% to 95%, 90% and return to 100% was recorded. Oxygen saturation from arterial blood samples (SartO2) was also measured at each time point respectively. The linear correlation coefficient of the regression analysis between SartO2 and SoesO2 was 0.954. The mean±2SD of the difference was 0.3%±4.3% for SoesO2vs. SartO2 and 6.8%±5.6% for SpulseO2vs. SartO2 (P<0.001). The 95% confidence interval for the absolute difference between SoesO2 and SartO2 was 0.3% to 0.7% and 6.2% to 7.4% between SpulseO2 and SartO2. The time to reach 90% saturation measured with SoesO2 was approximately 94 seconds earlier than the SpulseO2 (P<0.001). In conclusion, SoesO2 is more accurate and enables earlier detection of hypoxemia when compared to conventional pulse oximetry during hypoxemia for patients undergoing general anesthesia.

关键词： esophageal pulse oximetry     conventional pulse oximetry     hypoxemia    

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Telomeric impact of conventional chemotherapy

null

《医学前沿（英文）》 2013年 第7卷 第4期   页码 411-417 doi: 10.1007/s11684-013-0293-z

摘要：

The increased level of chromosome instability in cancer cells, leading to aneuploidy and gross chromosomal rearrangements, is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies (CT) kill cells by inducing a non-tolerable rate of DNA damage. A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic drugs. These results raise the interesting possibility that CT with genotoxic drugs preferentially target telomeres. In agreement with this view, accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT (stem cell transplantation) or non-myeloablative CT. However, almost nothing is known on the consequences of this shortening in terms of telomere stability, senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors (cognitive defect, fertility impairment, etc.). In this article, we propose: (1) telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance; (2) telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity; (3) the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.

关键词： telomere     antineoplasic drugs     conventional chemotherapies    

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Improvement in growth yield of single-walled carbon nanotubes with narrow chirality distribution by pulse

Bin Xu, Toshiro Kaneko, Toshiaki Kato

《化学科学与工程前沿（英文）》 2019年 第13卷 第3期   页码 485-492 doi: 10.1007/s11705-019-1831-2

摘要： A pulse plasma chemical vapor deposition (CVD) technique was developed for improving the growth yield of single-walled carbon nanotubes (SWNTs) with a narrow chirality distribution. The growth yield of the SWNTs could be improved by repetitive short duration pulse plasma CVD, while maintaining the initial narrow chirality distribution. Detailed growth dynamics is discussed based on a systematic investigation by changing the pulse parameters. The growth of SWNTs with a narrow chirality distribution could be controlled by the difference in the nucleation time required using catalysts comprising relatively small or large particles as the key factor. The nucleation can be controlled by adjusting the pulse on/off time ratio and the total processing time.

关键词： single-walled carbon nanotubes     chirality-controlled synthesis     pulse plasma chemical vapor deposition    

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A modified pulse charging method for lithium-ion batteries by considering stress evolution, charging

Yanfei ZHAO, Bo LU, Yicheng SONG, Junqian ZHANG

《结构与土木工程前沿（英文）》 2019年 第13卷 第2期   页码 294-302 doi: 10.1007/s11709-018-0460-z

摘要： The stress evolution, total charging time and capacity utilization of pulse charging (PC) method are investigated in this paper. It is found that compared to the conventional constant current (CC) charging method, the PC method can accelerate the charging process but will inevitably cause an increase in stress and a decrease in capacity. The charging speed for PC method can be estimated by the mean current. By introducing stress control, a modified PC method called the PCCC method, which starts with a PC operation followed by a CC operation, is proposed. The PCCC method not only can accelerate charging process but also can avoid the stress raising and capacity loss occurring in the PC method. Furthermore, the optimal pulsed current density and switch time in the PCCC method is also discussed.

关键词： fast charging method     pulse charging     stress evolution     charging time     capacity utilization    

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Oxygen reduction electrocatalysis: From conventional to single-atomic platinum-based catalysts for proton

《能源前沿（英文）》 doi: 10.1007/s11708-023-0907-3

摘要： Platinum (Pt)-based materials are still the most efficient and practical catalysts to drive the sluggish kinetics of cathodic oxygen reduction reaction (ORR) in proton exchange membrane fuel cells (PEMFCs). However, their catalysis and stability performance still need to be further improved in terms of corrosion of both carbon support and Pt catalyst particles as well as Pt loading reduction. Based on the developed synthetic strategies of alloying/nanostructuring Pt particles and modifying/innovating supports in developing conventional Pt-based catalysts, Pt single-atom catalysts (Pt SACs) as the recently burgeoning hot materials with a potential to achieve the maximum utilization of Pt are comprehensively reviewed in this paper. The design thoughts and synthesis of various isolated, alloyed, and nanoparticle-contained Pt SACs are summarized. The single-atomic Pt coordinating with non-metals and alloying with metals as well as the metal-support interactions of Pt single-atoms with carbon/non-carbon supports are emphasized in terms of the ORR activity and stability of the catalysts. To advance further research and development of Pt SACs for viable implementation in PEMFCs, various technical challenges and several potential research directions are outlined.

关键词： oxygen reduction electrocatalysis     Pt single-atom catalysts     conventional Pt-based catalysts     design thoughts and synthesis     metal-support interactions    

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Characteristics and energy distribution of modulated multi-pulse injection modes based diesel HCCI combustion

LIU Bin, SU Wanhua, WANG Hui, HUANG Haozhong

《能源前沿（英文）》 2007年 第1卷 第4期   页码 420-427 doi: 10.1007/s11708-007-0061-7

摘要： Cycle fuel energy distribution and combustion characteristics of early in-cylinder diesel homogenous charge compression ignition (HCCI) combustion organized by modulated multi-pulse injection modes are studied by the engine test.

关键词： combustion     compression     homogenous     in-cylinder     modulated multi-pulse    

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High frequency group pulse electrochemical machining

WU Gaoyang, ZHANG Zhijing, ZHANG Weimin, TANG Xinglun

《机械工程前沿（英文）》 2007年 第2卷 第3期   页码 293-296 doi: 10.1007/s11465-007-0051-5

摘要： In the process of machining ultrathin metal structure parts, the signal composition of high frequency group pulse, the influence of frequency to reverse current, and the design of the cathode in high frequency group pulse electrochemical machining (HGPECM) are discussed. The experiments on process were carried out. Results indicate that HGPECM can greatly improve the characteristics of the inter-electrode gap flow field, reduce electrode passivation, and obtain high machining quality. The machining quality is obviously improved by increasing the main pulse frequency. The dimensional accuracy reaches 30 40 ?m and the roughness attained is at 0.30 0.35 ?m. High frequency group pulse electrochemical machining can be successfully used in machining micro-parts.

关键词： HGPECM     process     machining quality     passivation     inter-electrode    

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Performance-based seismic assessment of a historical masonry arch bridge: Effect of pulse-like excitations

《结构与土木工程前沿（英文）》   页码 855-869 doi: 10.1007/s11709-023-0972-z

摘要： Seismic analysis of historical masonry bridges is important for authorities in all countries hosting such cultural heritage assets. The masonry arch bridge investigated in this study was built during the Roman period and is on the island of Rhodes, in Greece. Fifteen seismic records were considered and categorized as far-field, pulse-like near-field, and non-pulse-like near-field. The earthquake excitations were scaled to a target spectrum, and nonlinear time-history analyses were performed in the transverse direction. The performance levels were introduced based on the pushover curve, and the post-earthquake damage state of the bridge was examined. According to the results, pulse-like near-field events are more damaging than non-pulse-like near-field ground motions. Additionally the bridge is more vulnerable to far-field excitations than near-field events. Furthermore, the structure will suffer extensive post-earthquake damage and must be retrofitted.

关键词： masonry arch bridges     seismic behavior     modal properties     pulse-like records     nonlinear time history analysis    

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Techno-economic characteristics of wastewater treatment plants retrofitted from the conventional activated

《环境科学与工程前沿（英文）》 doi: 10.1007/s11783-021-1483-6

摘要：

While a growing number of wastewater treatment plants (WWTPs) are being retrofitted from the conventional activated sludge (CAS) process to the membrane bioreactor (MBR) process, the debate on the techno-economy of MBR vs. CAS has continued and calls for a thorough assessment based on techno-economic valuation.

关键词： Membrane bioreactor (MBR)     Conventional activated sludge (CAS)     Cost-benefit analysis     Data envelopment analysis     Net profit    

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A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

《信息与电子工程前沿（英文）》 2015年 第16卷 第12期   页码 1088-1098 doi: 10.1631/FITEE.1500111

摘要： With the continual increase in switching speed and rating of power semiconductors, the switching voltage spike becomes a serious problem. This paper describes a new technique of driving pulse edge modulation for insulated gate bipolar transistors (IGBTs). By modulating the density and width of the pulse trains, without regulating the hardware circuit, the slope of the gate driving voltage is controlled to change the switching speed. This technique is used in the driving circuit based on complex programmable logic devices (CPLDs), and the switching voltage spike of IGBTs can be restrained through software, which is easier and more flexible to adjust. Experimental results demonstrate the effectiveness and practicability of the proposed method.

关键词： Driving pulse edge modulation     Switching voltage spike     Complex programmable logic device (CPLD)     Active gate drive    

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Nonlinear experimental response of non-conventional composite steel and concrete connection

Tobia ZORDAN, Bruno BRISEGHELLA

《结构与土木工程前沿（英文）》 2009年 第3卷 第1期   页码 42-49 doi: 10.1007/s11709-008-0058-y

摘要： An experiment was carried out on a set of full-scale specimens of a non-conventional connection between a concrete column and a composite steel and concrete beam defined on the basis of a number of requirements. The proposed connection, conceived in the ambit of semi-rigid joints, is aimed at combining general ease of construction with a highly simplified assembly procedure with a satisfying transmission of hogging moment at supports in continuous beams. For this purpose, the traditional shear studs used at the interface between the steel beam and the upper concrete slab, are also employed at the ends of the steel profiles welded horizontally to the end plates. The test is aimed at investigating the hogging moment response of the connection under incremental loads until failure.

关键词： composite connections     nonlinear behaviour     hogging moment     monotonic tests    

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Innovative hybrid reinforcement constituting conventional longitudinal steel and FRP stirrups for improved

Mostafa FAKHARIFAR,Ahmad DALVAND,Mohammad K. SHARBATDAR,Genda CHEN,Lesley SNEED

《结构与土木工程前沿（英文）》 2016年 第10卷 第1期   页码 44-62 doi: 10.1007/s11709-015-0295-9

摘要： The use of fiber reinforced polymer (FRP) reinforcement is becoming increasingly attractive in construction of new structures. However, the inherent linear elastic behavior of FRP materials up to rupture is considered as a major drawback under seismic attacks when significant material inelasticity is required to dissipate the input energy through hysteretic cycles. Besides, cost considerations, including FRP material and construction of pre-fabricated FRP configurations, especially for stirrups, and probable damage to epoxy coated fibers when transported to the field are noticeable issues. The current research has proposed a novel economical hybrid reinforcement scheme for the next generation of infrastructures implementing on-site fabricated FRP stirrups comprised of FRP sheets. The hybrid reinforcement consists of conventional longitudinal steel reinforcement and FRP stirrups. The key feature of the proposed hybrid reinforcement is the enhanced strength and ductility owing to the considerable confining pressure provided by the FRP stirrups to the longitudinal steel reinforcement and core concrete. Reinforced concrete beam specimens and beam-column joint specimens were tested implementing the proposed hybrid reinforcement. The proposed hybrid reinforcement, when compared with conventional steel stirrups, is found to have higher strength, stiffness, and energy dissipation. Design methods, structural behavior, and applicability of the proposed hybrid reinforcement are discussed in detail in this paper.

关键词： FRP     ductility     confinement     seismic     shear    

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Energy distribution between liquid hydrogen and liquid oxygen temperatures in a Stirling/pulse tube refrigerator

《能源前沿（英文）》 2023年 第17卷 第4期   页码 516-526 doi: 10.1007/s11708-022-0844-6

摘要： A two-stage gas-coupled Stirling/pulse tube refrigerator (SPR), whose first and second stages respectively involve Stirling and pulse tube refrigeration cycles, is a very promising spaceborne refrigerator. The SPR has many advantages, such as a compact structure, high reliability, and high performance, and is expected to become an essential refrigerator for space applications. In research regarding gas-coupled regenerative refrigerator, the energy flow distribution between the two stages, and optimal phase difference between the pressure wave and volume flow, are two critical parameters that could widely influence refrigerator performance. The effects of displacer displacement on the pressure wave, phase difference, acoustic power distribution, and inter-stage cooling capacity shift of the SPR have been investigated experimentally. Notably, to obtain the maximum first-stage cooling capacity, an inflection point in displacement exists. When the displacer displacement is larger than the inflection point, the cooling capacity could be distributed between the first and second stages. In the present study, an SPR was designed and manufactured to work between the liquid hydrogen and liquid oxygen temperatures, which can be used to cool small-scale zero boil-off systems and space detectors. Under appropriate displacer displacement, the SPR can reach a no-load cooling temperature of 15.4 K and obtain 2.6 W cooling capacity at 70 K plus 0.1 W cooling capacity at 20 K with 160 W compressor input electric power.

关键词： Stirling/pulse tube refrigerator     displacer displacement     space application     phase shift     energy distribution    

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AGRI-ENVIRONMENTAL ASSESSMENT OF CONVENTIONAL AND ALTERNATIVE BIOENERGY CROPPING SYSTEMS PROMOTING BIOMASS

《农业科学与工程前沿（英文）》 2022年 第9卷 第2期   页码 284-294 doi: 10.15302/J-FASE-2021435

摘要：

Bioenergy, currently the largest renewable energy source in the EU (64% of the total renewable energy consumption), has sparked great interest to meet the 32% renewable resources for the 2030 bioeconomy goal. The design of innovative cropping systems informed by bioeconomy imperatives requires the evaluate of the effects of introducing crops for bioenergy into conventional crop rotations. This study aimed to assess the impacts of changes in conventional cropping systems in mixed dairy cattle farms redesigned to introduce bioenergy crops either by increasing the biomass production through an increase of cover crops, while keeping main feed/food crops, or by substituting food crops with an increase of the crop rotation length. The assessment is based on the comparison between conventional and innovative systems oriented to feed and biogas production, with and without tillage, to evaluate their agri-environmental performances (biomass production, nitrogen fertilization autonomy, greenhouse gas emissions and biogas production). The result showed higher values in the biogas cropping system than in the conventional and feed ones for all indicators, biomass productivity (27% and 20% higher, respectively), nitrogen fertilization autonomy (26% and 73% higher, respectively), methanogenic potential (77% and 41% higher, respectively) and greenhouse gas emissions (15% and 3% higher, respectively). There were no negative impacts of no-till compared to the tillage practice, for all tested variables. The biogas cropping system showed a better potential in terms of agri-environmental performance, although its greenhouse gas emissions were higher. Consequently, it would be appropriate to undertake a multicriteria assessment integrating agri-environmental, economic and social performances.

关键词： alternative cropping systems / bioeconomy / biogas / biomass production / fertilization autonomy / greenhouse gas assessment    

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A novel soft-switching twin arc pulse MAG welding inverter

WANG Zhenmin, XUE Jiaxiang, WANG Fuguang, HUANG Shisheng

《机械工程前沿（英文）》 2007年 第2卷 第2期   页码 224-227 doi: 10.1007/s11465-007-0039-1

摘要： The high-speed double wire pulse metal gas arc (MAG) welding process possesses advantages of automation and high efficiency and quality. Thus, it attracts much more attention nowadays. To meet the requirements of the double wire pulse MAG welding process, a novel double wire pulse MAG welding inverter integrated with technologies, such as soft-switching, double closed loop control, and synchronic control, is produced. A complete performance test was done for the pulsed MAG welding power supply by using a computer testing platform. The results of the experiment indicate that the novel welding inverter has an excellent performance both in the dynamic and the static characteristics. Also, the synchronic control between the master inverter and the slave inverter is reliable.

关键词： high-speed     control     computer     experiment indicate     platform    

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标题 作者 时间 类型 操作

Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

null

期刊论文

Telomeric impact of conventional chemotherapy

null

期刊论文

Improvement in growth yield of single-walled carbon nanotubes with narrow chirality distribution by pulse

Bin Xu, Toshiro Kaneko, Toshiaki Kato

期刊论文

A modified pulse charging method for lithium-ion batteries by considering stress evolution, charging

Yanfei ZHAO, Bo LU, Yicheng SONG, Junqian ZHANG

期刊论文

Oxygen reduction electrocatalysis: From conventional to single-atomic platinum-based catalysts for proton

期刊论文

Characteristics and energy distribution of modulated multi-pulse injection modes based diesel HCCI combustion

LIU Bin, SU Wanhua, WANG Hui, HUANG Haozhong

期刊论文

High frequency group pulse electrochemical machining

WU Gaoyang, ZHANG Zhijing, ZHANG Weimin, TANG Xinglun

期刊论文

Performance-based seismic assessment of a historical masonry arch bridge: Effect of pulse-like excitations

期刊论文

Techno-economic characteristics of wastewater treatment plants retrofitted from the conventional activated

期刊论文

A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

期刊论文

Nonlinear experimental response of non-conventional composite steel and concrete connection

Tobia ZORDAN, Bruno BRISEGHELLA

期刊论文

Innovative hybrid reinforcement constituting conventional longitudinal steel and FRP stirrups for improved

Mostafa FAKHARIFAR,Ahmad DALVAND,Mohammad K. SHARBATDAR,Genda CHEN,Lesley SNEED

期刊论文

Energy distribution between liquid hydrogen and liquid oxygen temperatures in a Stirling/pulse tube refrigerator

期刊论文

AGRI-ENVIRONMENTAL ASSESSMENT OF CONVENTIONAL AND ALTERNATIVE BIOENERGY CROPPING SYSTEMS PROMOTING BIOMASS

期刊论文

A novel soft-switching twin arc pulse MAG welding inverter

WANG Zhenmin, XUE Jiaxiang, WANG Fuguang, HUANG Shisheng

期刊论文